HFrEF Learning Center

Current mortality-reducing therapies target progressive neurohormonal, maladaptive responses

References

  1. Kemp CD, et al. Cardiovasc Pathol. 2012;21:365-371.
  2. Hartupee J, et al. Nat Rev Cardiol. 2017;14:30-38.
  3. Mann DL, et al. Heart failure and cor pulmonale. In: Longo DL, et al, eds. Harrison’s Principles of Internal Medicine. Vol II. 18th ed. New York, NY: McGraw-Hill; 2012:1901-1915.
  4. Hasenfuss G, et al. Pathophysiology of heart failure. Zipes DP, et al, eds. In: Braunwald’s Heart Disease. 11th ed. Philadelphia, PA: Elsevier Inc; 2019;442-461.
  5. Mann DL, et al. Circulation. 2005;111:2837-2849.
  6. van Bilsen M, et al. Eur J Heart Fail. 2017;19:1361-1378.
  7. Katz AM, et al. Eur Heart J. 2016;37:449-454.
  8. Rumsfeld JS, et al. Circulation. 2013;127:2233-2249.
  9. Wang Y, et al. J Am Heart Assoc. 2019;8:e012272. doi:10.1161/JAHA.119.012272
  10. Langenickel TH, et al. Drug Discov Today: Ther Strategies. 2014:e2-e9.
  11. Ma TK, et al. Br J Pharmacol. 2010;160:1273-1292.
  12. Shah A, et al. P T. 2017;42:464-472.
  13. Crowley SD, et al. Proc Natl Acad Sci U S A. 2006;103:17985-17990.
  14. Brown DA, et al. Nat Rev Cardiol. 2017;14:238-250.
  15. Volpe M, et al. Int J Mol Sci. 2019;20:2092. doi:10.3390/ijms20092092
  16. O’Connell J, et al. Int J Clin Cardiol Res. 2018;2:053-057.
  17. Sulfi S, et al. Int J Clin Pract. 2006;60:222-228.
  18. Yancy CW, et al. J Am Coll Cardiol. 2013;62:e147-e239.
  19. Yancy CW, et al. J Am Coll Cardiol. 2016;68:1476-1488.
  20. Kayani W, et al. Neurohormonal Blockade in Heart Failure. In: Baliga RR, et al, eds. Color Atlas and Synopsis of Heart Failure. New York, NY: McGraw-Hill; 2019.